The study included healthy, educated adults who took standard tests of memory, reasoning and perception at the outset and at some point over the next seven years.
出自-2016年6月阅读原文
英语六级真题
Concerns about open science should be discussed at the outset of a study.
2017年12月六级真题（第二套）阅读 Section B
柯林斯高阶英汉双解学习词典释义
PHRASE
在开始时/ 从一开始
If something happens at the outset of an event, process, or period of time, it happens at the beginning of it. If something happens from the outset it happens from the beginning and continues to happen.